Moonbeam says:
LOL! I can see him using it to pat-pat-pat the patient while occasionally saying "there, there," but because he doesn't really understand the proper inflection, it's actually unnerving rather than comforting. So he can't understand why he always has to use more than the usually required dose of anesthesia.
lavtodd says:
Ha! I mean, Cassano was probably whining while he was talking anyway.
If I may propose a new head-canon (which, coincidentally, helps the Zlambano ship),
Marbo always leaves one hand free so he can hold a patient's hand during surgery.
I love the concept of both of these. Even though hes not accustomed to human emotion, Marbo still tries his damn hardest to be empathetic when he can be, and holding a patients hand, even if it makes them uncomfortable, or patting their hair, is exactly something he would do.