Orobu says:
Ever played? I'm willing to learn with you, just wondering. It seems like a game that could allow a good amount of players. Is 2 enough?
SaighdearKit is my girlfriend and I have both ran and played Blades in the Dark. I've done a lot of campaigns in-person and only really one or two via text.
Like @rp_anon was saying, the big thing is figuring out how to do the discussion between the storyteller and the players to figure out position, effect, and possible consequences. I
strongly recommend having an OOC area or even having a Discord made to figure things out via text so it doesn't clog up the gameplay.
As for number of players, I tend to find that the game works best between two - four players. Lots of players means adding in additional options and the group can get paralyzed by options sometimes of how to best address a situation and making sure everyone has a chance to shine. With less people, the group has more limited options and specializations so they tend to have a more focused approach. You don't have to worry about making everyone shine.
I have ran a game where all four players were Cutters. The group really fit the whole "if all you have are hammers, everything is a nail" mentality.