Mr. Smith is too caught up in OmniCorp's protocols to evade Eliza's shotgun blast. (Or what he thinks are their protocols, since he's not actually an OmniCorp employee...there's a lot of stuff going on in his fake-but-also-sorta-real-stooge mind.)
The blast explodes out of the shotgun in a strange display of light and color. Sort of like something you see out of the corner of your eye, but when you try to focus on it, it's like it's not really there....
Pain rips through Mr. Smith's entire body, along with a sense of...unbeing. However, the blast doesn't draw blood, break bones, or anything like that, since it's actually an....
"Antimatter shotgun, baby! A few more hits, and you'll be nothing but a quantum uncertainty!"
She pumps the shotgun, ejecting a shell and loading another, and again aims it at Mr. Smith! While she does so, her robo-crew swarms the shapeshifter!