LC: Super Scrubs World Building

Because a game can never have too many threads... here's another, regarding world-building. (There can indeed be too many threads; I'll cool it soon. Forgive me... supers games excite me -- they are in my blood!)

Everyone please provide me with the following:

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1. A major city, anywhere in the world, that you wouldn't mind seeing destroyed in an alien invasion.

2. A major city, anywhere in the world, that you really -don't- want to see destroyed in an alien invasion.

3, A well-known landmark, anywhere in the world. Ancient, historic, recent -- anything goes.

4. A fictional / futuristic place or piece of advanced tech anywhere on the planet, the moon, or mars -- an advanced city, a skyship, an orbital elevator, an underwater colony, a space station, a pair of teleportation gates, etc.

5. The name of the International defense / crisis management / emergency response agency that two of our PCs have ties to.

Clarification -- these cities can be real or fictional. If the latter, just specify where they are and maybe a few words about why you hate 'em or love 'em.

Love this.
Cool. Floating... on the ocean? In the atmosphere?
KCC, BZ -- you both said this! Someone pick anew.
Oh yeah. This is totally a thing!

@LightOfMidnight , want to throw your ideas into the mix?

No worries, and YES! There -is- a fog between those dates!

Thanks for the responses!

So summing up:

Major Cities Y'all Don't Like: NYC, London, Moscow, DC, Vegas
Major Cities Y'all Like: Prague, Reykjavik, Paris, Berlin, Atlantis
Landmarks: The Space Needle, Stonehenge, The Statue of Liberty, The Pyramids at Giza, Niagara Falls
Futuristic Places: Solstice Station, Weather FROG, Cloud City, Portal to the Still Zone, The Beacon
The Defense Agency: A.E.G.I.S., CAIN, F.O.R.C.E., JANUS, D.A.T.A.

Sweet -- thanks for playing along, everyone. I can use all of the answers from the first four, but let's settle on the name of the agency you'll be working for. I'll put a poll up in Discord.