I wish you had brought it up up front, but I'm generally ok.
Here are some themes I would not be comfortable with:
- sexist/homophobic/transphobic ideas presented positively
- any real world religion presented as the one true religion
- realistic violence/torture/sexual violence, especially involving children
Themes I would like to see:
- The nature of humanity. Itari, being detached from humanity, but created by and given many of the values them, might struggle to know who/what he is. Think Data from star trek
For the record, technically Itari is either genderless or gender fluid, depending on your definition. He has no sex, he doesn't feel any intrinsic male or femaleness, and he changes presentations to suit the circumstances or his mood, as easily as a human changes cloths