That is one of the things that I find with Numenera. Its so vast and filled with wonder and strangeness, and it always piques my intellectual curiosity because I have no idea what anything is or how it works, and that's fascinating and refreshing. But at the same time, its SO non-traditionally alien that I always feel like a stranger or a tourist, rather than a resident there. It's hard to feel connected, or even pretend to feel connected to a place that's so many things at once. I'm not sure how to explain it any better, but it seems even more alien to me than the strangest sci-fi or science-fantasy - which it kind of is.... It's weird, I'm fascinated by the setting, but even when I'm playing in it, I feel apart from it.
Q, I think you're right. If a group did an extensive world-building Session 0 and at least had a connection to, and an understanding of a place, it would at least provide a 'reality spike' that could be an anchor as they go off into the strange and unknown.